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Polynucleotides

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Rather than adding volume or altering your facial structure, polynucleotides work to improve skin quality, elasticity and tissue repair at a cellular level, supporting your ongoing skin health.

At JB Aesthetics, polynucleotide treatments are always tailored to you. We take the time to understand what you would like to improve, and as a gentle, regenerative approach focused on supporting overall skin health, your skin will feel stronger, healthier and naturally refreshed.

At A Glance

TREATMENT TIME

30 minutes

NUMBING

Topical numbing cream if required

RECOVERY TIME

Immediate, with minimal downtime

RESULTS

Gradual improvement over several weeks, with optimal outcomes following a course of three treatments

What Are Polynucleotides?

Polynucleotides are naturally derived molecules that support your skin’s repair and renewal processes. When carefully injected into the skin by our doctors, they work by encouraging hydration and boosting collagen and elastin, helping your skin gradually feel stronger and healthier.

Over time, this can improve texture and overall skin quality in a subtle, natural way, which is why they are so well regarded at our clinic. They are particularly effective in delicate areas such as under the eyes and work well as part of your wider skincare and injectables journey.

Polynucleotide skin rejuvenation treatment London clinic

Benefits of Polynucleotides

Polynucleotides skin regeneration treatment London
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Stimulates Skin Regeneration

Encourages cellular repair and tissue renewal.

Improves Skin Elasticity & Texture

Supports firmer, smoother and more resilient skin.

Enhances Hydration

Improves moisture retention for healthier-looking skin.

Natural, Progressive Results

Results develop gradually while maintaining a natural appearance.

Polynucleotides for Men & Women

Polynucleotides are suitable for both men and women. Treatment plans are adapted to skin type, lifestyle and individual goals.

For men, treatment often focuses on improving skin resilience and texture while maintaining a natural, understated appearance.

For women, treatment may prioritise elasticity, hydration and overall skin rejuvenation.

The JB Aesthetics Approach to Polynucleotides

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Evidence-Based Practice

Treatments are guided by clinical evidence and best practice in aesthetic medicine.

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Bespoke Treatment Planning

Every plan is tailored to facial anatomy, muscle strength and individual goals.

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Conservative, Natural Results

The focus is on refreshing the face without stiffness or an artificial appearance.

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Patient Safety First

JB Aesthetics is a doctor-led clinic with extensive experience in facial anatomy and injectable treatments. Safety and suitability are prioritised throughout.

Aftercare Guidance

Polynucleotides consultation JB Aesthetics Marylebone
    • Alcohol and strenuous exercise for 24 hours

    • Excessive heat such as saunas and steam rooms for 24 hours

    • Applying pressure to or massaging treated areas unless advised by your clinician

    • Mild redness or swelling at injection sites may occur

    • Skin improvements develop gradually over time

    • Full aftercare instructions will be provided following treatment

Frequently Asked Questions
  • Polynucleotides can be used to treat a range of areas, including:

    • Face

    • Under-eye area

    • Neck

    • Décolletage

    • Hands

    Treatment areas are selected following a comprehensive skin assessment.

  • Polynucleotides may be suitable for patients who:

    • Notice thinning or crepey skin

    • Experience dullness or dehydration

    • Want to improve skin quality without filler

    • Are seeking a regenerative approach to ageing

    • Prefer subtle, long-term improvement

     

    A consultation is required to assess suitability and develop a bespoke treatment plan.

  • A course of three treatments is usually recommended for optimal results. This will be discussed during consultation.

  • Skin quality improvements develop gradually over several weeks as regeneration occurs.

  • No. Polynucleotides improve skin quality without adding volume or altering facial shape.

  • When administered by qualified doctors, polynucleotides are considered safe and well tolerated.

  • Yes. Polynucleotides are commonly used in the under-eye area where the skin is delicate.

  • Yes. They are often combined with Profhilo, Sunekos or other regenerative skin treatments.

Patient Reviews

JB Aesthetics is proud to hold a five-star rating on Google, with patients consistently praising the clinic’s professionalism, honesty and considered approach to facial aesthetics.

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Book a Polynucleotides
Consultation in Marylebone

Polynucleotides at JB Aesthetics are ideal for patients seeking regenerative skin improvement delivered through a considered, doctor-led approach.

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